5 Essential Elements For cees dekker

5 Essential Elements For cees dekker

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Using one-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic elements of the composition and dynamics of chromosomes. Our exploration passions include:

But how can morality, the dignity with the human being, my experience of your indicating of existence, adhere to within the movement of atoms? A purely naturalistic perspective fails in this article; a Christian viewpoint, I think, is a way more affordable solution to interpret these components of actuality.’

Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins

Unfortunately, For several years following Iijima’s report, the manufacture of clean nanotubes was cumbersome. In 1996, even so, the team of Richard Smalley at Rice University managed to make single-walled carbon nanotubes at substantial yield. Shortly just after, I contacted Smalley, and we decided to be part of forces to evaluate the transport by way of a single carbon nanotube.

2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial ever review in the dynamics DNA supercoils and the invention of supercoil hopping

The coiled-coil of your human Rad50 DNA mend protein consists of specific segments of enhanced flexibility

We use nanofabricated microfluidic buildings to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which assess the basic function of spatial confinement in the molecular and cellular amount. Our jobs involve the subsequent:

Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.

‘You should not just take into consideration the queries of tomorrow, but in addition look at the issues with the working day soon after tomorrow’

‘The fantastically refined way where aspects in character perform never ceases to amaze me. If we address the puzzle of how lifetime came into becoming, I expect that my amazement within the complexity of development can have elevated and with it my awe with the greatness on the Creator.’

Case in point (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in gray, the rim with the pore is highlighted in purple, as well as a 3D rendering on the motion of the DNA rod is exhibited.

2006, to start with demonstration of molecular sorting inside a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and initially estimate of electrokinetic Electrical power conversion inside a nanofluidic channel

Electrical transportation in monolayers ceesdekker.net of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes

It had been an exceedingly fascinating time, for the duration of which I been given plenty of guidance from Delft College of Technologies, the place I had been a professor at the time, and I commenced various collaborations with molecular biologists. That helped me discover a good deal.’